Comparison of online pharmacies by Drug: Generic Lopressor (Metoprolol)
What is Lopressor?
Lopressor (Metoprolol), a type of medication known as a beta-blocker, is used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), and heart attack. When prescribed for high blood pressure, it is effective when used alone or in combination with other high blood pressure medications. ). Beta-blockers work by affecting the response to nerve impulses in certain parts of the body. As a result, they decrease the heart’s need for blood and oxygen by reducing its workload. They also help the heart to beat more regularly.
Adults
Do not stop taking metoprolol without talking to your doctor first. If metoprolol is stopped suddenly, it may cause chest pain or heart attack in some people.
Doses of Metoprolol should be individualized by your doctor. It should be taken with or immediately following meals.
High Blood Pressure
The usual starting dosage of Metoprolol is a total of 100 milligrams a day taken in 1 or 2 doses, whether taken alone or with a diuretic. Your doctor may gradually increase the dosage up to 400 milligrams a day. Generally, the effectiveness of each dosage increase will be seen within a week.
Angina Pectoris
The usual starting dosage is a total of 100 milligrams a day taken in 2 doses of Metoprolol. Your doctor may gradually increase the dosage up to 400 milligrams a day.
Generally, the effectiveness of each dosage increase will be seen within a week. If treatment is to be discontinued, Metoprolol should be withdrawn gradually over a period of 1 to 2 weeks.
Heart Attack
Metoprolol can be used for the treatment of heart attack both in the hospital during the early phases and after the individual’s condition has stabilized. Your doctor will determine the dosage according to your needs.
Side Effects
The nervous system and sensory organs: at least 10% – weakness; 1-9,9% – dizziness and headache; 0,1-0,9% – reduction of concentration, sleepiness/insomnia, nightmares, depression, muscle convulsions, paresthesia, 0,01-0,09% – nervousness, anxiety, weakening of libido, impaired vision, xerophthalmia, conjunctivitis, less than 0.01% – weakness, fatigue, anxiety, confusion, amnesia / short-term memory loss, hallucinations, tinnitus, impaired taste oschuscheniy. So the cardiovascular system and blood (hematopoiesis, hemostasis): 1-9,9% – bradycardia, palpitations, hypotension, cold extremities, and in 0,1-0,9% – heart failure, AV block, edematous syndrome, chest pain at 0,01-0,09% – reduction of myocardial contractility, arrhythmias, less than 0,01% – gangrene (in patients with severe peripheral circulation), myocardial conduction disturbances, syncope, thrombocytopenia, leukopenia, agranulotsitoz. So the digestive tract: 1-9,9% – nausea, abdominal pain, diarrhea or constipation; 0,1-0,9% – vomiting 0,01-0,09% – dry in the mouth, liver function, bloating, indigestion, heartburn, gepatit. So the respiratory system: dyspnea (1-9,9%), bronchospasm (0,1-0,9%), vasomotor rhinitis (0,01 – 0,09%), dispnoe. So the skin: 0,1-0,9% – rash, dystrophic skin changes, 0,01-0,09% – reversible alopecia; less than 0,01% – photosensitivity, exacerbation of psoriasis , itching, erythema, urticaria, gipergidroz. Prochie: reduction in body weight (0,1-0,9%), arthralgia, arthritis, myalgia, muscle weakness, Peyronie’s disease.
7 Bizarre Side Effects of Metoprolol, Link on Video (Dr. Sam Bailey):
https://www.youtube.com/watch?v=O9WZkEYcMy0
Overdose
Symptoms: hypotension, acute heart failure, bradycardia, heart block, AV block, cardiogenic shock, bronchospasm, respiratory failure, and consciousness/coma, nausea, vomiting, generalized convulsions, cyanosis (manifest in 20 minutes – 2 hours after admission). Treatment: gastric lavage, symptomatic treatment: atropine sulfate (w / fast 0,5-2 mg) – at a bradycardia and a violation of AV conduction, glucagon (1-10 mg IV, then IV infusion 2-2,5 mg / h), and dobutamine – in the case of a reduction of myocardial contractility; agonists (noradrenaline, adrenaline, etc.) – with arterial hypotension, diazepam (IV slowly) – to eliminate seizures; inhaled beta-agonists or IV jet introduction of aminophylline for relief bronhospasticheskih reactions pacing.
Drug Interactions
Sympatholytic potentiate hypotension, nifedipine, nitroglycerin, diuretics, etc. apressin antihypertensive drugs. Antiarrhythmic and anesthetic facilities increase the risk of bradycardia, arrhythmia, hypotension. Digitalis drugs potentiate slowing AV conduction. Simultaneously, intravenous verapamil and diltiazem may cause cardiac arrest. Beta-adrenoceptor agonists, aminophylline, cocaine, estrogens, indomethacin, and other NSAIDs impair the antihypertensive effect. Enhances and prolongs the action antidepolyarizuyuschih muscle relaxants. Combination with alcohol leads to the mutual reinforcement of inhibitory effects on the CNS. Allergens increased the risk of severe systemic allergic reactions or anaphylaxis. Alter the effectiveness of insulin and oral antidiabetic drugs and increases the risk of hypoglycemia. Antacids, hydralazine, oral contraceptives, cimetidine, ranitidine, phenothiazines – raise the level of metoprolol in the blood, Rifampicin – reduces. Lowers the Cl of lidocaine, the effectiveness of beta_2-agonists (to increase the dose of the latter). Incompatible with MAO inhibitors of type A.
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